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Wednesday, August 11, 2010

Peritoneal mesothelioma cancer - symptoms & treatment options

Peritoneal mesothelioma, also known as asbestos lung cancer, is a relatively uncommon form of mesothelioma cancer, accounting for less than a quarter of all mesothelioma cases. It is called peritoneal because it appears as a tumor in the peritoneum membrane of the abdomen.
Causes

Exposure to asbestos is the only known cause of this disease in the USA. Patients afflicted with Peritoneal Mesothelioma have inhaled or swallowed asbestos fibers usually through work related activities. Symptoms do not occur until 20 to 40 years after contact with the mineral and its by products. Malignant peritoneal mesothelioma is often fatal and patients who are afflicted by it live on average of less than a year from the time of their diagnosis.
Symptoms of Peritoneal Mesothelioma

Symptoms may include abdominal pain, abdominal swelling, a change in your bowel habits, such as more frequent diarrhea or constipation, lumps of tissue in the abdomen and unexplained weight loss.
Diagnostic Tools

Peritoneal Mesothelioma is first detected by X-rays or CT scans, peritoneoscopy (analysis of the peritoneum) or a biopsy where a tissue sample in taken for examination by a pathologist.
Treatment Options

Localized treatments treat only the original cancer site by either surgery or radiotherapy. A peritonectomy is a surgery used when peritoneal mesothelioma is detected early on. However, the symptoms are usually detected only in the most advanced stages because of the gradual development of symptoms. Complete removal of the caner through surgery is doubtful even in the earliest stages of the disease. The first 30 days following surgery are crucial. Unfortunately, the post surgery death rate for this operation is very high. Many patients do not make it through the procedure. With this in mind, many medical centers do not choose surgery as a viable treatment option plan at this time.
Regional chemotherapy is used in peritoneal mesothelioma cases, when the cancer is still localized at its point of origin. This option treatment is employed in both early and late stages of the disease using anti-cancer drugs. The drugs are injected directly into the abdomen. Patients undergo weekly or biweekly treatments depending upon the specific drugs used.
An additional procedure known as adjuvant chemotherapy, (regional chemotherapy) can be used directly following surgery in order to reduce the likelihood of the cancer returning. However, when the cancer cannot be entirely removed through surgery, chemotherapy will continue throughout the existence of the cancer in an attempt to slow its development.
A second type of treatment known as systemic treatments are used when the cancer has metastasized (spread throughout the body). Systematic treatments are implemented in either earlier stages or late stages of peritoneal mesothelioma.
Since peritoneal mesothelioma often remains dormant for years, the cancer is usually detected in its end stages. At this point patients are too ill to handle intensive chemotherapy. Doctors choose non-aggressive palliative care mesothelioma treatments at this time. Treatment goals are concentrated on remedying pain, discomfort and weight loss rather than attacking the disease head on. One type of pain common in the late states of this disease is caused by fluid buildup inside the abdomen. Doctors will attempt to reduce the pain and discomfort by draining the excess fluid through a procedure called abdominal paracentesis.

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